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We spoke with Brodie Lancaster ahead of her appearance at the  launch of the  highly anticipated 2016 Emerging Writers’ Festival Program.  A superstar in our eyes, we can’t wait to hear her talk to us all about failure and ambition at The Wheeler Centre on 10 May.

You are performing at our Program Launch: ‘Halfway Between the Gutter and the Stars’. Do you have moments you think about that encapsulate this theme in your own life?
You’ll have to hear my talk at the Program Launch to know the answer to that!
JK, but kind of. I guess all those in-between moments of limbo I’ve had in my life—times when I decided to move across the world or cut ties with someone or start (or quit) a big project—present that opportunity to either succeed or fail spectacularly. The decisions we make during those cloudy moments are what I think about when I hear the phrase, Halfway Between the Gutter and the Stars.

You do a lot – you founded the zine Filmme Fatales, you’re senior editor of The Good Copy, you write stuff yourself and have contributed to publications widely, plus more – how do you juggle all these things and transition between hats?
It’s not super glamorous or inspiring, but I don’t do much more but work. Even right now, I’m writing these answers as I go HAM on my inbox on an Amtrak from Portland to Seattle, where I’m giving a big talk tomorrow. But ultimately, everything I do kiiiiinda connects in some way, so each disparate job helps another.
The Good Copy is my day job—I’m a senior editor there and I work on editorial copywriting projects from nine to five—and it helps to keep my brain active and work out my technical writing muscles.
I put that exercise into practice when it comes to freelancing and I need to take feedback, be concise and clear in my arguments and phrase juuust the right tweet to share stuff I’ve written. (lol)
I work on Filmme Fatales both at work (it’s published by The Good Copy) and during any moment of downtime I have.
Oh, and I’m also trying to write a book right now hahahaha. I know.

What have you been working on lately?
I’m at the end of a two-month trip around America right now. While here, I’ve been covering the SXSW Film program for Filmme Fatales, I gave a talk in New York City and I’m about to give a talk on fangirls and One Direction at the EMP Pop Conference in Seattle. After that, I’m going to be taking a week in LA to work on my book a little more before I come home and get back into everything I talked about doing in the previous question.

What are you excited by in the Australian literary landscape at the moment?
Without sounding like a douchey name-dropper, I’m excited by how many people I know (or even just people my age, with similar levels of writing and life experience as I have) have books out that I can buy and read, and that so many other people can too! The first thing I’m doing when I get home is buying Jennifer Down’s Our Magic Hour; I just saw Omar Musa’s book Here Come The Dogs at Powell’s in Portland; Minna Gilligan’s Time After Time, which came out last year, is one of my favourite non-fiction books. As someone who is trying to write a book right now and who never ever thought I would or could or should write a book, it’s encouraging and invigorating to read incredible work by people who make that feel possible.

Have you any advice for fellow writers?
I have a lot! But real quick, I think it is very important to remember to write what you know and like, and not what you think you’re supposed to be writing for whatever trend/style/internetty reason.

What aspects of the Emerging Writers’ Festival do you look forward to?
I love seeing everyone from Twitter IRL!!!!!! Also I really love the diversity of the programming (shoutout to me and my fellow cute’n’smart members of this year’s Programming Advisory Committee) and the commitment EWF has always had to programming people who aren’t just ~big names~; I always hear about or meet people at the festival whose work I didn’t know about before the event takes place.

Brodie Lancaster is the editor of Filmme Fatales, a zine about women and cinema, and a senior editor at The Good Copy, a writing studio in Collingwood. 

She has written for Rookie, Rolling Stone, Pitchfork, Vulture and other publications. Her first book, a pop culture memoir called No Way! Okay, Fine!, will be out next year with Hachette.

Early Bird Tickets to The National Writers’ Conference are available now. Taking place over two days, with over seventy speakers, The National Writers’ Conference features panels, conversations, and performances, allowing you meet this year’s Ambassadors and other writers from around Australia.

Golden Tickets to the Emerging Writers’ Festival are also available now. Golden Tickets are your passport to the Emerging Writers’ Festival. They will give you access to the National Writers’ Conference, plus the rest of the festival including all panels, talks, performances and selected workshops.

The 2016 Emerging Writers’ Festival program launches on Tuesday, 10 May at The Wheeler Centre.

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Bupropion: The Australian Doctor’s Guide to Reclaiming Energy, Mood and Control After 30

Attention: If you are over 30 and find yourself exhausted despite a full night’s sleep, struggling to focus at work, feeling flat or unmotivated, carrying extra weight from previous antidepressants, or still reaching for a cigarette despite knowing the risks — you are not alone. Many Australians feel trapped in a cycle of low mood, fatigue and broken confidence. The good news is that there is a medication that works differently: bupropion.

As a doctor, I see patients every week who have tried standard antidepressants and felt worse — numb, foggy, gaining weight, losing their sex drive. Bupropion offers a genuinely different path. It is an energising, weight-neutral medication that can lift mood, sharpen focus, and even help you quit smoking. Below, I explain how it works, who it suits, and how to access it safely in Australia.

What Makes Bupropion Different?

Bupropion is a noradrenaline-dopamine reuptake inhibitor (NDRI). While most antidepressants (SSRIs like sertraline or escitalopram) mainly boost serotonin, bupropion increases noradrenaline and dopamine — the brain chemicals linked to energy, motivation, concentration and reward. This means many people experience more mental clarity, less emotional blunting, and a better sex life compared with older antidepressants.

Table 1: Bupropion at a Glance for Australian Patients
Feature Key Fact
Drug class Noradrenaline-dopamine reuptake inhibitor (NDRI)
Main uses in Australia Major depression (often prescribed off-label), smoking cessation (TGA-approved as Zyban)
Common benefits Improved energy, better focus, lower risk of sexual side effects, weight neutral or mild weight loss
Key contraindications Bulimia nervosa, anorexia nervosa, seizure disorders, abrupt alcohol or benzodiazepine withdrawal
Legal status Prescription-only (Schedule 4); PBS subsidised mainly for smoking cessation, private script for depression

Interest: Is Bupropion Right for You?

If you are over 30 and have been let down by other treatments, bupropion may address several common pain points at once. Many of my patients describe feeling “switched on” again — able to get out of bed, focus on work, enjoy intimacy and avoid the weight gain that often accompanies SSRIs. It is also one of the few antidepressants that can actively help with smoking cessation, making it a smart choice if you are trying to quit.

However, bupropion is not for everyone. Below I answer the most important safety questions so you can have an informed conversation with your own doctor.

What Is the Contraindication with Bulimia?

Bupropion must not be used in people with a history of bulimia nervosa or anorexia nervosa. The reason is that both conditions cause major electrolyte imbalances — particularly low potassium and magnesium — which lower the seizure threshold. Because bupropion also lowers the seizure threshold, combining the two significantly increases the risk of a seizure. Even if you are currently in recovery, your doctor will need to carefully assess your history. This is an absolute safety rule, not a minor caution.

Should I Avoid Caffeine While Taking Bupropion?

You do not need to eliminate caffeine completely, but moderation is key. Bupropion is an activating medication, meaning it can make you feel more alert — sometimes too alert. Adding high doses of caffeine (energy drinks, multiple strong coffees) can worsen side effects like jitteriness, racing heart, insomnia and anxiety. I usually advise patients to limit themselves to 1–2 standard coffees or teas per day and avoid caffeine after midday. If you notice anxiety or poor sleep, cut back further. For most people, a morning coffee is fine.

Can Bupropion Be Used in Patients with Seizure Disorders?

No. Bupropion is contraindicated in patients with a seizure disorder (epilepsy) or any condition that significantly lowers the seizure threshold. This includes a history of head trauma, brain tumour, or severe alcohol withdrawal. The seizure risk is dose-dependent, which is why the maximum recommended dose for depression is usually 300 mg per day in Australia — and why the dose is always increased slowly. If you have ever had a seizure, your doctor will likely choose a different medication.

Can Bupropion Cause Anxiety?

Yes, bupropion can cause or worsen anxiety, especially in the first few weeks. Because it boosts noradrenaline and dopamine, some people feel more “wired,” restless or irritable initially. This usually settles as the brain adjusts, but for people with significant generalised anxiety or panic disorder, bupropion may not be the first choice. If anxiety appears, your doctor may lower the dose, suggest taking it early in the morning, and advise reducing caffeine. For many patients, the lifting of depression actually reduces overall anxiety after 2–4 weeks, but this needs to be monitored closely.

What Are the Legal Considerations for Prescribing Bupropion in Australia?

In Australia, bupropion is a Schedule 4 prescription-only medicine. It is TGA-approved as Zyban for smoking cessation. For depression, it is often prescribed off-label, which is legal and common when a doctor judges it clinically appropriate. However, PBS subsidy for bupropion is generally limited to smoking cessation; a script for depression is usually a private prescription, meaning you pay the full pharmacy price rather than the PBS-subsidised price. Your doctor should explain this cost difference. There is no restriction on prescribing bupropion for depression, but the prescriber must document the clinical rationale and obtain your informed consent, especially given the seizure risk.

What Is the Role of Bupropion in Fibromyalgia Treatment?

Fibromyalgia causes widespread pain, fatigue, brain fog and sleep disturbance — and depression commonly overlaps. While bupropion is not first-line for fibromyalgia, it can play a useful off-label role, particularly for the fatigue, low energy and cognitive fog that many fibromyalgia patients find debilitating. Some small studies and clinical experience suggest bupropion improves energy and motivation more than traditional pain medications. It does not directly treat pain, but by lifting mood and boosting dopamine, it can make the condition far easier to manage. It is often considered after or alongside duloxetine, pregabalin or amitriptyline.

What Mobile Apps or Programs Support Bupropion Treatment in Australia?

Supporting your treatment with the right tools can significantly improve outcomes. In Australia, several free and low-cost digital resources can help you track progress, manage side effects and stay on track:

How to Find a Doctor Who Prescribes Bupropion in Australia

Your first step is your GP. Book a long consultation, explain your symptoms and treatment history, and mention that you would like to discuss bupropion. Your GP can assess whether it is safe for you and either prescribe it or refer you to a psychiatrist with expertise in mood disorders. You can also use the Healthdirect service finder or the RANZCP Find a Psychiatrist directory to locate a specialist. Many telehealth services now offer bulk-billed mental health consultations, making it easier than ever to get an expert opinion without leaving home.

Desire: Imagine Your Life with More Energy and Clarity

Picture waking up after a full night’s sleep and actually feeling rested. Imagine enjoying your work again, feeling present with your family, and not dreading the side effects that made you feel like a zombie. Picture losing the stubborn weight, rekindling intimacy, and finally stubbing out that cigarette for good. This is what many Australians over 30 achieve with bupropion when it is prescribed appropriately and taken under medical supervision.

Table 2: Bupropion vs Common SSRIs — What Matters After 30
Feature Bupropion (NDRI) Typical SSRIs (e.g. sertraline, escitalopram)
Energy Usually increased Often neutral or sedating
Weight Weight neutral or mild loss Often weight gain
Sexual function Low risk of dysfunction High risk of dysfunction
Effect on smoking Reduces cravings No direct effect
Anxiety risk Can increase initially Often reduces anxiety

Of course, bupropion is not a magic pill. It requires a careful assessment, gradual dose adjustment, and honest communication with your doctor. But for many people — especially those who have struggled with fatigue, weight gain, low libido and treatment-resistant depression — it is a genuine turning point.

Action: Take the Next Step Today

If you recognise yourself in this article, do not wait another month feeling stuck. Here is exactly what to do:

  1. Book a long GP appointment — ask for a mental health assessment and discuss whether bupropion is suitable for you.
  2. Ask about a Mental Health Care Plan — this gives you access to Medicare-subsidised psychological support alongside medication.
  3. Be honest about your history — mention any eating disorder, seizures, head injury, caffeine intake, anxiety or smoking habits.
  4. Discuss cost — ask whether your script will be PBS-subsidised or private, and consider generic options if available.
  5. Download a support app — set up My Health Record and a medication reminder today.
  6. Start the conversation — you can even bring this article to your appointment to help explain what you are looking for.

You deserve to feel energised, clear-headed and in control again. Bupropion may not be for everyone, but for the right person, it can be the difference between merely existing and truly living. Talk to your Australian GP or psychiatrist today and take the first step toward a brighter, more focused future.



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